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AminoCarnitines - Delivering L-Carnitine for Maximum Performance

Feel the power of science - feel the science of power! Life Extension Optimized Carnitine with GlycoCarn® and ArginoCarn® combines three advanced forms of carnitine in one single formula to help transport fatty acids right to the heart of your energy-producing mitochondria. Life Extesion PEAK ATP® with GlycoCarn® provides two critical nutrients that augments endothelial nitric oxide synthesis, enhancingblood flow to active tissues. (read more)



Boost Your Energy - Optimize Your Energy Output

Science based premium quality High performance nutritional supplements Naturally from Life Extension. Combat muscle fatigue with Optimized Carnitne with GlycoCarn®. Carnitine is an amino acid that promotes the burning of fat for fuel in the mitochondria. (read more)



Carnitine - The Energy Powerhouse

Weight gain and increased lipid levels are too often accepted by Americans as an unfortunate side effect of the aging process; however, since these devastating characteristics of the human life cycle take place on a cellular level, they can be fought on a cellular level as well. (read more)



Muscle Science Roundup

A supplement that appears to boost NO an average of 18 percent above baseline is propionate L-carnitine and glycine, sold as GPLC, which boosts NO–synthesizing enzymes in the lining of blood vessels. You need 4.5 grams a day divided into two doses. It’s best taken with a high-carb source, as the increased insulin release helps muscle retain carnitine.(read more)


Question to the PROCreator:
"I know you advocate the use of GlycoCarn. I’m curious what dosage is ideal, and when you should take it?"

This is one product that I have witnessed some very significant results with. Bodybuilders experience lower lactic acid levels, increased recovery, and pumps that literally last all day— as opposed to the hour or two (at most) you will see, even with the best arginine-based nitric oxide products... (read more)


Pump It Up With GPLC and NO

What is NO? It’s a key molecule that is manufactured in the body and plays numerous roles in nearly all physiological systems. In the cardiovascular system it is a vasodilator, which means it expands the internal diameter of blood vessels. Vasodilation leads to an increase in blood flow, oxygen transport and delivery of nutrients to surrounding tissue, including skeletal muscle... (read more)


Get Ripped, Not Ripped Off!

GlycoCarn® is a major active ingredient now appearing within the most currently updated scientific formulations of nutritional powders, capsules and beverages which claim to support maximal nitric oxide (NO) retention before, during and after strenuous workouts and muscle recovery... (see the ad)

GlycoCarn® Improves High Intensity Exercise Performance

The AminoCarnitines® marketed through Sigma-Tau Health-Science are molecularly bonded forms of L-carnitine along with
specific carnitine precursor amino acids. Over the past few years Sigma-Tau has provided research funding to study the metabolic
effects of GlycoCarn® (Glycine-Propionyl-L-Carnitine HCL... (read more)
(posted with the permission of Life Extension Magazine)

The Pro Creator

The impetus to write this article came after
Something else I have been experimenting with among my clients is the new production patented USP-verified and Informed Choice-Sport® certified dietary supplement Glycine Propionyl-L-Carnitine hydrochloride (GPLC) that is manufactured under the registered tradename GlycoCarn®... (read more

Super Power Nitric Oxide Stimulation

Apart from Mickey Rourke, the comeback of the decade belongs to carnitine. Originally lauded for it's fat-loss benefits, it can also function as a natural antioxidant, research shows. What's more, recent evidence points to one form of carnitine - glycine propionyl-l-carnitine (GPLC) - as being a potent nitric oxide stimulator... (read more)


Glycine propionyl-L-carnitine, or GPLC, is a molecular-bonded form of propionyl-L-carnitine and the amino acid glycine. We have demonstrated an increase in blood levels of NOx, a surrogate marker of NO, with oral GPLC intake of 4.5 grams a day.15 Our findings agree with recent work in which investigators demonstrated an increase in blood NOx in subjects who received six grams per day of propionyl-L-carnitine intravenously... (read more)

AminoCarnitines® for
Human Health and Performance

Energy. Stamina. Vitality. Health. How does one achieve these desired outcomes? The best approach for most individuals involves the performance of exercise on most—if not all—days of the week. Dietary intake along with regular, consistent sleep, plus relaxation and motivation is of crucial importance to living a productive life. Another strategy is to use certain nutritional supplements, such as L-carnitine... (read more)


Acetyl-L-Carnitine Arginate Dihydrochloride (ArginoCarn®):
Metabolic Effects in Human Subjects

Dietary supplementation with the nutrient L-carnitine has been extensively studied, in particular as related to fatty acid metabolism and antioxidant activity. New research over the past few years has revealed additional roles for L-carnitine, including positive effects on muscle recovery from strenuous exercise, as well as improved blood flow, possibly mediated by enhanced production/bioavailability of nitric oxide. In relation to the latter, such variables have traditionally been measured in a fasted/rested state... (read more)
(posted with the permission of Life Extension Magazine)

Nitric oxide stimulating dietary
where is the evidence?
Nitric oxide supplements

Dietary supplements purported to increase nitric oxide production have gained enormous popularity within the athletic (e.g., bodybuilding) community in recent years. Although anecdotal reports suggest a potential benefit from using such products, the scientific evidence is sparse. To the knowledge of this author, only one ingredient consumed in oral form by human subjects has been reported within the scientific literature to promote an increase in blood nitric oxide. This ingredient is a unique form of L-carnitine called glycine propionyl-L-carnitine (GPLC). This article discusses the scientific evidence for nutritional supplements to increase nitric oxide production, as well as the physiological rationale as to why nitric oxide may be important related to athletic performance. Directions for future scientific work in this area of sport supplementation are presented... (read more)

Rising Stars in the Nutrition World

After completing a New Dietary Ingredient submission to the FDA, Kaneka Nutrients L.P. (Pasadena, TX) launched ubiquinol into the marketplace as Kaneka QH. I first wrote about this antioxidant form of Coenzyme Q10 (CoQ10) in the March 2007 issue of WholeFoods Magazine, simply reporting on work done by scientists worldwide. By now, there are well over 30 brands selling ubiquinol in a variety of strengths and servings...(read more)


Rising Stars in the Nutrition World

The impetus to write this article came after
a recent discussion with the owner of a chain of stores. Bluntly, he asked me if there was a need for yet another brand, as I showed him a new product line. For me, and the excited sales clerk who lined up the meeting, it’s not about anything but new products. For many of us, our first introduction to this industry can be traced back to a new product that enhanced our lives. That’s the excitement I feel for these new products, which are the new rising stars in the nutrition world.. Another nutrient with multiple benefits is glycine-propionyl-l-carnitine (GPLC)... (read more)

GPLC Increases Nitric Oxide
in Bodybuilders

A study from the university of Memphis. led by Richard Bloomer, found that Glycine Propionyl-L-Carnitine (GPLC) supplements (GlycoCarn; 3 grams per day combined with 1,044 miligrams of glycine for four weeks) increased NO production in weight trained men... (read more)

Understanding L-Carnitine

Carnitine exists in two isomeric forms: l-carnitine and d-carnitine. The latter has no physiological role other than acting as a competitive inhibitor of l-carnitine, the only isomer biologically active and with a fundamental role in the utilization of lipid substrates by the cellular mitochondria. There are in the marketplace other sources of d- or dl-carnitine of highly improbable efficacy and, in the case of d-carnitine, not allowed for food or feed use. Sigma-Tau HealthScience does not now nor has it ever been a supplier of any forms of carnitine other than the pure l-carnitine form. L, dl- and l-isomers can be distinguished optically by using refractometric techniques that determine the specific rotation and therefore the optical purity of the isomer. Sigma-Tau HealthScience l-carnitine meets or exceeds all USP as well as other existing codex requirements for optical purity and, of course, other codex parameters. (read more)


Glycine Propionyl-L-Carnitine HCL, (GlycoCarn®) for Human Health and Performance

Dietary supplementation with the naturally occurring nutrient L-carnitine has been extensively studied as an aid to improve fatty acid metabolism and aerobic exercise capacity, to provide antioxidant benefits, and to enhance blood flow to active tissues (e.g., skeletal muscle and heart). While multiple forms of carnitine have been studied and are currently available, Propionyl-L-Carnitine (PLC) has been shown to best support healthy heart and skeletal muscle function. A patented and safe USP dietary form of PLC has been developed which is molecularly bonded to glycine, one of the precursor amino acids to carnitine biosynthesis. This form is known as Glycine Propionyl-LCarnitine (GPLC) or GlycoCarn®, and is one of the AminoCarnitines® branded and marketed by Sigma-Tau HealthScience. (read more)
(posted with the permission of Life Extension Magazine)


Glycine Propionyl-L-Carnitine HCL, (GlycoCarn®) for Human Health and Performance

Dietary supplementation with the naturally occurring nutrient L-carnitine has been extensively studied as an aid to improve fatty acid metabolism and aerobic exercise capacity, to provide antioxidant benefits, and to enhance blood flow to active tissues (e.g., skeletal muscle and heart). While multiple forms of carnitine have been studied and are currently available, Propionyl-L-Carnitine (PLC) has been shown to best support healthy heart and skeletal muscle function... (read more)


The New L-Carnitine With a Focus on Muscle and Energy

Sometimes, a well-known and valued supplement can be transformed to provide significant new benefits. Such is the case with L-carnitine. Propionyl-L-carnitine is a form that until very recently was restricted to medical uses. Now it finally is available more generally as glycine propionyl-L-carnitine or Glycocarn®, which is a patented compound. Many health food shoppers will be surprised by the difference found with this next generation of L-carnitine. This is the L-carnitine with a focus on muscular energy, exercise recovery and reduced fatigue. (read more)

Metabolic Cardiology - It's All About ATP - Part 2

Last month we chatted with Dr. Stephen Sinatra about new nutrients to keep the heart and arteries healthy, particularly a nutrient called propionyl- L-carnitine (PLC). This month, we will focus on metabolic cardiology and how adenosine triphosphate (ATP), and thus its precursors, the carnitines, CoQ-10 and D-ribose, is the bottom line in heart health. Anybody with any type of cardiovascular disease has a heart that is always leaking ATP. The body can’t make it back fast enough by de novo (from the beginning) synthesis! It takes too long and the ATP leakage is faster. It’s all about ATP and less about oxygen! (read more)



Optimized Carnitine with GlycoCarn

Controlled Labs Blue Gene